Startup Database

Vertical AI Startups 2026 (149 companies)

This page lists all 149 vertical ai startups in the AIToolGuide 2026 startups database, taken from the 2026 cohort: Y Combinator's four 2026 batches and the TrustMRR and Indie Hackers listings. The biggest intake here is YC Summer 2026 with 59 companies, and 128 of the 149 list a headquarters in USA. Every listing is free and ranked by the data, not by payment. Click any company for its story, founders and facts.

All 149 vertical ai startups in the 2026 database, newest batch first.
CompanyWhat it doesBatchHQ
Aikido TechnologiesClean marine AI datacentersYC Fall 2026San Francisco, CA, USA; Remote
AilitElectrifying North American freight rail with swappable batteries.YC Fall 2026San Francisco, CA, USA
BlinkaBanking for US companies operating globallyYC Fall 2026San Francisco, CA, USA
CanosAI-powered blood test to detect cancer in dogs (and cats soon).YC Fall 2026Oxford, England, United Kingdom
Cardinal SquareAI-native schoolsYC Fall 2026San Francisco, CA, USA
CesaraFaster & accurate transactions for health systemsYC Fall 2026San Francisco, CA, USA
ClaimKitAI-native tax firmYC Fall 2026San Francisco, CA, USA
CleanWe predict when a company is about to buy.YC Fall 2026San Francisco, CA, USA
CollarAI-Native Investor RelationsYC Fall 2026San Francisco, CA, USA
ConfettiBuild hardware projects using plain-English promptsYC Fall 2026San Francisco, CA, USA
CONUSThe AI knowledge layer for medical devicesYC Fall 2026Cologne, NRW, Germany
DecentYour health plan should get better year-round. Not just once a year.YC Fall 2026San Francisco, CA, USA
DydemaA consumer brain-computer interface you can map to anything.YC Fall 2026San Francisco, CA, USA
erndThe Credit Card for the AI stackYC Fall 2026San Francisco, CA, USA
FleetyFleety is an AI dispatcher for plumbing and HVAC companies.YC Fall 2026San Francisco, CA, USA
ForwardOrigination network for private credit fundsYC Fall 2026San Francisco, CA, USA
GradonLegora for AEC (Architecture, Engineering, & Construction) firmsYC Fall 2026San Francisco, CA, USA
Halmos LabsMaximum information per experiment, minimum experiments per conclusionYC Fall 2026Lund, Skåne County, Sweden
Helios IntelligenceAt-home molecular body test: 1,000+ biomarkers from a drop of bloodYC Fall 2026Boston, MA, USA
Ignition BenefitsThe AI-Native Benefits BrokerageYC Fall 2026Los Angeles, CA, USA
InvertixAI that operates power plantsYC Fall 2026Munich, BY, Germany
Kairos HealthAI front desk that fills every chair for dental practicesYC Fall 2026San Francisco, CA, USA
MeltyMashup any gameYC Fall 2026San Francisco, CA, USA
NativeArtificial Intuition for marketingYC Fall 2026San Francisco, CA, USA
OpenScaffoldSuperagent for Deployment TeamsYC Fall 2026San Francisco, CA, USA
OpEraThe AI decision engine for factories, warehouses and fleetsYC Fall 2026San Francisco, CA, USA
OrganizelyA New AI-Native ERP for American Manufacturers 🇺🇸YC Fall 2026San Francisco, CA, USA
Perceptual LabsBuilding the next generation of visual intelligenceYC Fall 2026San Francisco, CA, USA
PetrichorWet lab infrastructure that turns AI experiments into training data.YC Fall 2026San Francisco, CA, USA
PlekMaps what employees do and what it costsYC Fall 2026San Francisco, CA, USA
ProtoA design tool with the accuracy of Cursor & creative freedom of FigmaYC Fall 2026San Francisco, CA, USA
QuippyHelps build social skills through daily practiceYC Fall 2026San Francisco, CA, USA
ReconeroReconero helps police officers automate their workflows with AIYC Fall 2026San Francisco, CA, USA
Redoubt InsuranceCommercial insurance for small businessesYC Fall 2026Salt Lake City, UT, USA
Resin TechnologiesResin helps engineers design electronics faster and more reliablyYC Fall 2026San Francisco, CA, USA
RomaRoma is the to-do list that does itselfYC Fall 2026
SaccadeWorld's Earliest Test for Alzheimer's BiomarkersYC Fall 2026San Francisco, CA, USA
Shire IntelligenceShire uses CCTV to run restaurants in real time.YC Fall 2026Myrtle Beach, SC, USA
SintropixAutonomous accounting platform for global companiesYC Fall 2026Santiago, Santiago Metropolitan Region, Chile
Taan.aithe most precise & controllable foundation music modelsYC Fall 2026San Francisco, CA, USA
TalosPredictive maintenance for power infrastructure.YC Fall 2026Baltimore, MD, USA
TelamontSentry for errors in construction documentsYC Fall 2026San Francisco, CA, USA
Viraj AeroNext generation gas turbines for data centers & aviationYC Fall 2026
VoreliosAI that can engineer anythingYC Fall 2026San Francisco, CA, USA
YamAI-powered dating sims for womenYC Fall 2026San Francisco, CA, USA
83 SciencesAI-native materials discovery powered by unpublished experimental dataYC Summer 2026San Francisco, CA, USA
Akon LabsDatabricks for Enterprise CodebasesYC Summer 2026San Francisco, CA, USA
Allia HealthAI-Native Medical Group for Mental HealthYC Summer 2026San Francisco, CA, USA
AllooviumThe company brain for construction companiesYC Summer 2026San Francisco, CA, USA
ArbitalThe social trading app for stocks, memes, and perpsYC Summer 2026San Francisco, CA, USA
Atlas DiscoveryAI-native pharma companyYC Summer 2026San Francisco, CA, USA
AudunAI-native debt collection companyYC Summer 2026Oslo, Oslo, Norway
AxelrodHotels that run themselvesYC Summer 2026San Francisco, CA, USA
BernardAI employees that run home appliance repair companiesYC Summer 2026New York City, NY, USA
Billow AI LabsAI-native Accounting Firm that's killing DeloitteYC Summer 2026San Francisco, CA, USA
BizmarkOpenClaw for manufacturersYC Summer 2026San Francisco, CA, USA
BloomyAI-native learning for every schoolYC Summer 2026San Francisco, CA, USA
Callbook AIAI collections agency for late stage portfoliosYC Summer 2026San Francisco, CA, USA; Remote
CarSignalThe AI Operating System for Auto Shops.YC Summer 2026San Francisco, CA, USA
COACHThe AI Coach for in person sales reps.YC Summer 2026San Francisco, CA, USA
ComputableDerivatives Exchange for ComputeYC Summer 2026New York City, NY, USA
CovaFinancial infrastructure for family caregivingYC Summer 2026San Francisco, CA, USA
CueBenchRL post-training for science reasoning and performance engineeringYC Summer 2026San Francisco, CA, USA
DentaFortune 500 Dental BenefitsYC Summer 2026San Francisco, CA, USA
Dipole LabsAI-controlled optical switching for AI clustersYC Summer 2026Boston, MA, USA
DonkeyThe AI-native trading company: factory prices, delivered, one numberYC Summer 2026San Francisco, CA, USA
EdviroAI That Operates Energy InfrastructureYC Summer 2026San Francisco, CA, USA
Egoist MachinesYour personal context, securely portable across every AI app.YC Summer 2026San Francisco, CA, USA
Ekho LabsWorld Model for FreightYC Summer 2026New York City, NY, USA
ErinysWe help lawyers start and scale AI-native law firms.YC Summer 2026San Francisco, CA, USA
ExosatBuilding a neutral, sovereign alternative to StarlinkYC Summer 2026San Francisco, CA, USA
Experiential LabsOpen source AI gateway that turns your traffic into better modelsYC Summer 2026San Francisco, CA, USA
FlorinFlorin is an AI-native insurance company that runs autonomouslyYC Summer 2026San Francisco, CA, USA
Frontier ComputingFrontier grows scalable biological brains as an ML training substrateYC Summer 2026London, England, United Kingdom
GamgeeCuring cancer. Starting with dogs.YC Summer 2026San Francisco, CA, USA; Remote
GUILDMaking Defense Manufacturing Faster and CheaperYC Summer 2026New York City, NY, USA
Illume Labs24/7 Personal Health & Longevity CompanionYC Summer 2026San Francisco, CA, USA
Induction LabsBuilding intellectually curious AIYC Summer 2026San Francisco, CA, USA
InsurfThe AI-Native Decision Layer for Health InsuranceYC Summer 2026Providence, RI, USA
KebraAI For The Skilled WorkforceYC Summer 2026San Francisco, CA, USA
LemonLimeFully automated GTM for small businessYC Summer 2026San Francisco, CA, USA
Levocred AIAI Workforce for lendersYC Summer 2026San Francisco, CA, USA
LockeThe AI-native firm for public influence.YC Summer 2026San Francisco, CA, USA
LumeriaOura Ring for SkinYC Summer 2026San Francisco, CA, USA
MarbleThe autonomous back-of-house for restaurants.YC Summer 2026New York City, NY, USA
MarengoAI-Native Engineering Firm designing Data CentersYC Summer 2026San Francisco, CA, USA
MochiWatch and create animeYC Summer 2026Los Angeles, CA, USA
MusicArenaThe crowdsourced benchmark for AI-generated music and music productionYC Summer 2026San Francisco, CA, USA
OmantaA research lab for oneYC Summer 2026San Francisco, CA, USA
OpenTagModel Agnostic AI coworker in SlackYC Summer 2026San Francisco, CA, USA
PaletteThe Media Engine of the AI EraYC Summer 2026San Francisco, CA, USA
PennantThe World Model for Corporate GovernanceYC Summer 2026New York City, NY, USA
Perceptron MLWe make law firms AI-native.YC Summer 2026San Francisco, CA, USA
PetrarchAdvancing model capabilities for critical infrastructureYC Summer 2026San Francisco, CA, USA
Prodigy ResearchTraining the world's best AI model for quantitative finance.YC Summer 2026San Francisco, CA, USA
RationalFirst Zero-human Accounting FirmYC Summer 2026San Francisco, CA, USA
rekursiv.aiScale AI scientists whose own breakthroughs accelerate the next.YC Summer 2026San Francisco, CA, USA
SkymerseAutopilot for Flight OperationsYC Summer 2026San Francisco, CA, USA
SnowstoneAI-Driven Value Creation and Margin Expansion for Private EquityYC Summer 2026San Francisco, CA, USA
Standard MachinesTeaching AI to Design ChipsYC Summer 2026San Francisco, CA, USA
Tarifflo Inc.Supply chain compliance and cost savingsYC Summer 2026Salt Lake City, UT, USA
TorusSuperintelligence for InfrastructureYC Summer 2026San Francisco, CA, USA
WonderingDuolingo for learning anythingYC Summer 2026San Francisco, CA, USA
WonderTxExtrapolative AI to unlock First-in-Class drugsYC Summer 2026San Francisco, CA, USA; Remote
AbInitio BioThe Intelligence layer for Drug ManufacturingYC Spring 2026Boston, MA, USA
AGI Deploy CoDiffusing AI into critical industriesYC Spring 2026San Francisco, CA, USA
FinalDoseProgrammable DNA drug destroying all cancers, unlocking 80% of targetsYC Spring 2026Oxford, England, United Kingdom
GBrainA personal or team assistant that works while you sleepYC Spring 2026San Francisco, CA, USA
HedgeAI-Native insurance companyYC Spring 2026San Francisco, CA, USA
HyperCompany brain that powers your AI employeesYC Spring 2026San Francisco, CA, USA
ImperfectAdaptive training coach for runners, cyclists, and triathletesYC Spring 2026San Francisco, CA, USA
InferaControl lab instruments with natural language.YC Spring 2026San Francisco, CA, USA
KimptonLive Evaluation Arenas for Financial WorkYC Spring 2026New York City, NY, USA; Remote
MasterpieceWorking capital for data companies training frontier AIYC Spring 2026New York City, NY, USA
ModernModern automates the entire order-to-cash process for B2B companies.YC Spring 2026Melbourne, VIC, Australia
PanaceaAI-Native FDA Regulatory ServicesYC Spring 2026San Francisco, CA, USA
PopsCreate & play AI games with friendsYC Spring 2026New York City, NY, USA
RevnuYour AI growth hire.YC Spring 2026Manchester, England, United Kingdom
RudusAI Takeoffs for ConcreteYC Spring 2026San Francisco, CA, USA
Uno WalletThe AI mobile wallet that replaces Apple PayYC Spring 2026San Francisco, CA, USA
10x ScienceThe AI-native platform for next-generation protein characterization.YC Winter 2026San Francisco, CA, USA
AxionOrbital SpaceFoundation models for 24/7 Earth ObservationYC Winter 2026San Francisco, CA, USA
AxisAn AI Copilot for Trading DesksYC Winter 2026New York City, NY, USA
Beacon HealthAI Employees for Primary CareYC Winter 2026San Francisco, CA, USA
Bubble LabThe intelligence layer for communities and events.YC Winter 2026San Francisco, CA, USA
Carrot LabsAI Cost Management: Track and attribute AI spend across every providerYC Winter 2026San Francisco, CA, USA
ClaimGlideAI automated prior-auths for private medical practicesYC Winter 2026San Francisco, CA, USA
Condor EnergySoftware for enterprise energy procurement.YC Winter 2026Paris, Île-de-France, France
EnvariantInterpretability and reasoning infra for foundation models.YC Winter 2026San Francisco, CA, USA
ForemanKeeping contractors on the job site, not behind a desk.YC Winter 2026San Francisco, CA, USA
InstinctTrade with superhuman instinctYC Winter 2026San Francisco, CA, USA
InventoryQuantWe automate the inventory process in insuranceYC Winter 2026San Francisco, CA, USA
MartiniAI Video Production for ProfessionalsYC Winter 2026San Francisco, CA, USA
NdeaBuilding AGI that can innovate.YC Winter 2026Remote
OssusIntelligence for cultural institutionsYC Winter 2026San Francisco, CA, USA
OxusAI-powered automation for internal audit workflowsYC Winter 2026San Francisco, CA, USA
PantaAI Native Commercial Insurance BrokerageYC Winter 2026San Francisco, CA, USA
Pax HistoriaThe first AI-powered worldbuilding and gameplay platformYC Winter 2026San Francisco, CA, USA
PollenAI employees trained on your firm's workflows.YC Winter 2026San Francisco, CA, USA
Q2QWe help private equity teams find acquisition targets fasterYC Winter 2026San Francisco, CA, USA
RevionIntelligence for Automotive OperationsYC Winter 2026New York City, NY, USA
SideKitConsumer app studio.YC Winter 2026Toronto, ON, Canada
Strand AIMultimodal foundation models to predict uncollected patient biologyYC Winter 2026San Francisco, CA, USA
Synthetic SciencesInfrastructure for Autonomous ScienceYC Winter 2026San Francisco, CA, USA
Terranox AIThe first AI-powered uranium discovery companyYC Winter 2026San Francisco, CA, USA
The Token CompanyCompression middleware that improves LLM outputsYC Winter 2026San Francisco, CA, USA
Velum LabsThe OS for data quality across any stackYC Winter 2026San Francisco, CA, USA
Visibl SemiconductorsCustom silicon for power electronicsYC Winter 2026San Francisco, CA, USA
Voxel EnergyEnergy independent data centers with solar and repurposed batteries.YC Winter 2026

Browse the other categories

AI Agent Startups (137) AI DevTools Startups (58) AI Robotics Startups (51) AI Infrastructure Startups (29) AI Security Startups (25) AI Voice and Audio Startups (17) AI Vision Startups (10) AI Data Startups (8) More AI Startups (29)

Source: AIToolGuide 2026 startups database (513 AI companies), compiled from Y Combinator 2026 batch listings and the TrustMRR and Indie Hackers marketplaces, November 2026.

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